Contrast enhanced ultrasound ceus is the application of ultrasound contrast medium to traditional medical sonography ultrasound contrast agents rely on the different ways in which sound waves are reflected from interfaces between substances this may be the surface of a small air bubble or a more complex structure. Discover nonlinear ultrasound contrast agent imaging quantify relative perfusion and study biomarker expression with ease microbubble contrast agents have been used in ultrasound imaging as a means of improving the visualization of blood flow with respect to the surrounding tissue. Contrast enhanced ultrasound ceus involves the administration of intravenous contrast agents containing microbubbles of gas first generation ultrasound contrast agents contained microbubbles of air that were dissolved in blood when exposed to acoustic pressure in the ultrasound field. Ultrasound contrast media is used to increase the contrast of the sonogram image by enhancing the reflection of the ultrasound waves this occurs due to the difference in the ability of the contrast media and the soft tissue to reflect the ultrasound wave
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